VRAM is the quiet way a graphics card fails: the frame rate looks fine, then textures pop in and the game stutters. For a big open world it matters, so do not ignore it when you shop.
For GTA 6 planning, treat 4 GB as high risk, 6 GB as tight, 8 GB as the safe floor for 1080p, and 12 GB or more as real headroom. This is predicted, so pair the number with a readiness check before you buy.
Do not buy on a guess. Check your exact setup in 60 seconds and see the one part that matters.
predicted:FrameReady Can I Run tool. FrameReady uses predicted PC targets until official PC requirements or measured benchmarks are available.
official:Rockstar Games GTA VI page. Rockstar lists GTA VI for PlayStation 5 and Xbox Series X|S. FrameReady does not treat PC requirements as official until a PC source exists.